390 ACKNOWLEDGEMENTS The authors would like to thank the funding granted through the “CONYCIT, FONDEF/Primer Concurso IDeA de I+D, FONDEF/CONICYT 2018, ID18I10189” and the “ANID, Subdirección de Investigación Aplicada/Décimo Concurso de Investigación Tecnológica 2021/ FONDEF IT21I0043”. We also thank the company MSTECK SpA, which has sponsored and financed part of these studies. REFERENCES Cacciuttolo, C., & Cano, D. (2022). Environmental impact assessment of mine tailings spill considering metallurgical processes of gold and copper mining: Case studies in the Andean countries of Chile and Peru. Water, 14(19), 3057. https://doi.org/10.3390/w14193057 Cave, M. R., Rosende, M., Mounteney, I., Gardner, A., Miro, M. Environ. Sci. Technol. New insights into the reliability of automatic dynamic methods for oral bioaccessibility testing: A case study for BGS102 soil. (2016). 50(17), 9479–9486. DOI: https://doi.org/10.1021/acs.est.6b02387 Denys, S., Caboche J., Tack K. , Rychen G., Wragg J., Cave, M., Jondreville, C, Feidt C. Environ. Sci. Technol. In vivo Validation of the Unified BARGE Method to assess the Bioaccessibility of Arsenic 2 Antimony, Cadmium and Lead in soils. (2012) 46(11), 6252–6260. DOI: 10.1021/es3006942. Hamilton, E. M., Barlow, T. S., Gowing, C. J. B., Watts, M. J. Microchem. J. Bioaccessibility performance data for fifty-seven elements in guidance material BGS 102. (2015). 123, 131–138. DOI: https://doi.org/10.1016/j.microc.2015.06.001 ISO. Soil quality -- Assessment of human exposure from intake of soil and soil material -- Procedure for the estimation of the human bioaccessibility/bioavailability of metals in soil, ISO 17924: 2018. International Organization for Standardization, Geneva, Switzerland, 2018. Ma J, Li Y, Liu Y, Lin C, Cheng H (2019). Effects of soil particle size on metal bioaccessibility and health risk assessment. Ecotoxicol Environ Saf.;186:109748. https://doi.org/10.1016/j.ecoenv.2019.109748
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